解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科，口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学，全科和内科
医学，法律
医学，研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学，核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学，临床
abstract：:Tolerance was induced in Lewis (LEW) rat renal allograft recipients of Brown Norway kidneys by multiple pretransplant donor-blood transfusions and prior limited cyclosporine A. Rat renal allograft tolerance was associated with the induction of systemic donor T cells (10%), an early phase of nonspecific suppressor-cell...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/s0041-1345(97)00284-4
更新日期：1997-06-01 00:00:00
abstract：:In the same animal, following HS and recovery, pancreatic islet function remains intact while immunologic functions are impaired. Cellular responses to thermal stresses are complex and tissue specific. ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/s0041-1345(97)00225-x
更新日期：1997-06-01 00:00:00
abstract：:By understanding the size and characteristics of the potential donor pool, the concentration and location of the potential donors and factors influencing low rates of donation, it is possible to identify opportunities to improve the organ donation system. The exact donor gap needs to be established for each hospital/a...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0041-1345(96)00691-4
更新日期：1997-02-01 00:00:00
abstract：:Overall, the results seen in this study are encouraging. In this high-risk group of patients where the expected disease rate would normally be at least 55% to 60% without prophylaxis, a combination protocol of GCV, ACV, and CMVIG limited the rate of disease to 19%. When disease occurred, it was generally mild and easi...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1996-12-01 00:00:00
abstract：:As initially predicted by in vitro and animal model experiments, MMF appears to demonstrate significant potential as a new immunosuppressive drug. Early clinical trials have shown that MMF can be used effectively to prevent allograft rejection, and to treat allograft rejection, in heart, liver, and kidney transplant p...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1996-12-01 00:00:00
abstract：:In a country undergoing socioeconomic transformation, with all the attendant financial difficulties, it is rather difficult to obtain very good results in this expensive and advanced method of therapy. However, in spite of such difficulties, the results obtained are equal to the European standards, with 85% and 65% on...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Diarrhea is a frequent complication of small bowel transplantation in patients and experimental models. Although there are many potential causes, the underlying basis for most are not fully understood. Improved therapeutic approaches will come about through better understanding of mechanisms of bowel adaptation and re...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:In summary, synthetic peptides corresponding to linear sequences of HLA class I molecules can inhibit T-cell responses in vitro and in vivo. These peptides induce immunologic tolerance by binding to hsp-70 family members, causing an increase in intracellular calcium, and down-regulating the nuclear factor of activated...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1996-08-01 00:00:00
abstract：:Significant islet allograft prolongation was achieved by ICAM-1/LFA-1 blockade. ICAM-1 antisense oligonucleotide IP-3082 was effective in improving islet function as well as prolonging graft survival. ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Liver sinusoidal washout cells are low responders to mitogens, and suppressive in autologous PBM, and portal blood mononuclear cells, PHA supplemented, and autologous mixed lymphocyte cultures. They are less immunogenic after IV administration into allogeneic recipients than PBM, which could be measured in an in vivo ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:The current results of the present series demonstrate that intestinal allografts are more vulnerable to rejection and continue to be at a significantly higher risk long after transplantation compared with isolated liver allograft recipients. Unexpectedly, a combined liver allograft does not protect small bowel from re...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:There has been remarkable consistency in our laboratory for the experimental results derived from a variety of allogeneic and xenogeneic models of organ transplantation using BQR, a primary immunosuppressive agent, to prevent graft rejection. Considerable knowledge exists in a number of species with respect to the dos...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：:This report describes the clinical characteristics and demographics of patients enrolled into this rescue trial for patients experiencing refractory rejection after liver transplantation. Actuarial graft and patient survival at 12 months postconversion was 50% and 72%, respectively. Actual treatment success at 3 month...
journal_title：Transplantation proceedings
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1993-02-01 00:00:00
abstract：:1. A National Transplantation Service has been established at the Alfred Hospital performing more than 50 transplants per year. 2. Increased access to transplantation technology has facilitated an improvement in national population servicing from 2.7 to 6.2 transplants per million population per year. National funding...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Patients treated at the Royal Hospital in Oman during January-June 1991 were divided in 3 groups. The 1st group included 103 patients (49 males, 54 females, with a mean of 39 years) who attended the Nephrology Clinic and none of whom were on dialysis. In the 2nd group there were 102 patients (46 males, 56 females, w...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:The FCL provides support for clinical trials of FK 506 in liver transplantation by monitoring drug concentrations in plasma and whole blood. The sensitive EIA method of Tamura et al was adapted for routine use. Extraction of drug from 300 microL plasma or 20 microL whole blood samples was carried out using MeCl. An al...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:The delayed contralateral nephrectomy procedure (three-step) produced inconsistent results, indicating that the preserved autotransplanted kidney tends to remain unfunctional and to regenerate incompletely unless the demand for work is placed upon it. Omission of HES in UW (UW-plain) did not affect preservation succes...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:There was no statistical significance to the differences in waiting time for cadaveric renal transplant by race. Whether for first transplant or second or greater, any differences in waiting time could not be accounted for by the recipient's race. CAUC made up 58% of the waiting list, 65% of the recipients, and 87% of...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:In summary, we believe that our experience with concomitant use of OKT3 and either reduced-dose CyA for treatment of renal allograft rejections or full-dose CyA therapy for treatment of liver allograft rejection is both safe and possibly more effective in reversing allograft rejection than use of the antibody alone. T...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:The studies discussed in this presentation have shown that CD8 T lymphocytes have a primary role in conferring resistance to MCMV in the immunocompetent BALB/c mouse. In the presence of selective CD8 deficiency, however, other mechanisms, apparently mediated by the CD4 T-cell subset, contribute in a compensatory fashi...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1991-06-01 00:00:00
abstract：:An account is given of the 6- to 12-month survival, and causes of failure in 110 consecutive patients who underwent primary liver transplantation under treatment from the outset with FK 506 and steroids. The patient survival is 92.7%, and the first graft survival is 87.3%. At a very high frequency, the patients achiev...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Skin allografts were not enhanced by prior conditioning of blood and CyA (5 or 10 mg/kg/d). However, when BM-CyA pretreatment was used, SA survival was significantly prolonged (CyA, 5 or 10 mg/kg/d). In examining differences between the BT-CyA and BM-CyA protocols, equivocal levels of donor microchimerism (1.5%) were ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Prolonged liver preservation (up to 17 hours) with UW solution had no adverse effect on perioperative blood loss or results of postoperative serum biochemistry studies. After use of this solution, biliary and vascular complications as well as evidence of histologic damage were less. The advantages of the extended pres...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Our concepts of autoimmune disease have evolved with our changing understanding of the immune response. In recent years, clonal deletion theories have gradually given way to more dynamic views of the regulation of anti-self immune reactions. It is now clear that self-reactive B cells and some self-reactive T cells per...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1988-06-01 00:00:00
abstract：:The efficacy of bromocriptine, chloroquine, and Cs was quantitated in an in vitro system, with the use of mitogen-stimulated human PBMC. A concentration-dependent effect was found for each drug. Based on counts of blast cells, Cs was roughly 70 times more effective than either bromocriptine or chloroquine. Besides qua...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：:In principle, cell-mediated allograft rejection can be brought about by cytotoxic T cells or by a DTH-like reaction. The first part of this article reviews the relative importance of these two mechanisms in graft rejection and concludes that the bulk of evidence points to cytotoxic T cells as being of major importance...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1988-04-01 00:00:00
abstract：:PAP of harvested livers is routinely used to minimize parenchymal anoxia during storage. PP is compared with PAP to evaluate the relative reliability of PAP. Sixty female Landrace pigs were used for 30 OLTs. Group 1 livers underwent PP, whereas group 2 livers were treated with PAP. The cold ischemic time was less than...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：:In summary, we could not document an increased incidence of HA nor a detrimental effect of CyA use in our recipients of ABO-unmatched LRD kidneys. Thus, it would appear that the incidence of HA in this situation is low enough that no special pretreatment of the kidney transplant or recipient is warranted. Since the lo...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1987-12-01 00:00:00
abstract：:FK is a potent immunosuppressive agent. FK can be analyzed in biologic fluids by EIA. The oral absorption of FK is rapid but variable in dogs. After intramuscular administration, FK is slowly and continuously absorbed. FK is primarily eliminated by metabolism. Less than 1% of the administered dose is excreted in the b...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:These results suggest (1) that ALS + BM fractions can be used to promote tolerance in long-term graft survivors; (2) that the presence of apparent BM cells of donor origin in the allograft in normally functioning kidneys may be related to the mechanism of allograft prolongation, and (3) that some promise of possible s...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:The definition of CsA-induced nephrotoxicity is defined as impairment of renal function after transplantation exclusive of allograft rejection, vascular obstruction, and ureteral obstruction. This imprecise definition is one of exclusion and requires a careful clinical assessment of the patient, using information from...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:Eighty-seven organ transplant recipients developed 88 tumors after immunosuppression with CsA. The neoplasms showed important differences from those seen following conventional immunosuppressive therapy (CIT). Malignancies appeared an average of 14 months (range, 1 to 82) after CsA and 59 months (range, 1.0 to 225.5) ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:The serendipitous discovery of a new species of fungi T inflatum Gams coupled with the diligent investigations of Borel to dissect the immunosuppressive action of CsA have yielded a new reagent of compelling therapeutic moment. Due to its relatively specific inhibition of lymphokine generation by T helper cells, the d...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1985-08-01 00:00:00
abstract：:Two young men developed nephrotic syndrome associated with Hodgkin's lymphoma and progressive renal failure. After a short course of hemodialysis with blood transfusion, each received a cadaveric renal transplant. During the postoperative period, chemotherapy (MOPP) was given. No transplant rejection episodes were dia...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:To avoid nephrotoxicity and hepatotoxicity the CsA-PL should be kept at less than 500 ng/mL during the first month after transplantation and less than 200 ng/mL after four months. After ten months most patients in this study had a CsA-PL of less than 150 ng/mL and many had levels of less than 50 ng/mL with an apparent...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:Rat 13762NF mammary adenocarcinoma mimics human breast cancer in its pathology and pathogenesis. We selected and cloned spontaneously metastasizing variant tumor cell lines that spread from mammary fat pad subcutaneous sites to regional lymph nodes and lung. The biologic properties of these tumor clones changed during...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1984-04-01 00:00:00
abstract：:The pancreas of the dog was divided into segments of left lobe (tail), body and uncinate, but with in-situ blood supply to each segment intact, and comparisons within the same dog were made of various techniques of handling the pancreatic duct. Ligating the duct or allowing it to drain freely into the peritoneal cavit...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1982-12-01 00:00:00
abstract：:Prospective pretreatment with deliberate DST has afforded MLC reactive related donor-recipient pairs enhanced opportunity for successful transplantation. The sensitization rate in patients receiving DST prior to primary transplantation was 30%, but this sensitization has been generally specific and narrow-those patien...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：:Pre-BTs significantly improve the survival rate for first cadaver transplants, by a mechanism that remains obscure. The maximal influence is seen with smaller numbers of pre-BTs (1-5 units), but is also observed with larger numbers of pre-BTs. The possible beneficial influence of Tx-BTs on graft survival is not proven...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：:Following adoptive transfer into irradiated recipients, thymocytes can be induced to respond strongly to vaccinia virus. High levels of cytotoxic T-lymphocyte (CTL) activity may be generated from thymus, but not from spleen, of 3-day-old mice. The capacity of thymocytes to differentiate into effector CTL tends to be l...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1981-12-01 00:00:00
